Villa Cetinale is a 17th century villa in the Ancaiano district near Siena, Italy.

Designed by the architect Carlo Fontana, in the Roman Baroque style, the villa was built in 1680 by Cardinal Flavio Chigi for Pope Alexander VII — Fabio Chigi. The gardens at Villa Cetinale are renowned as being amongst the most beautiful in Italy. Within easy reach of Florence, Siena, Pisa, Rome, Villa Cetinale is ideally situated for sightseeing, shopping, eating out or just relaxing in the beautiful Tuscan landscape.